Dr. Zbigniew Wszolek, MD

• Electrodiagnostic Medicine

• Neurology

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• University Of Iowa Hospitals And Clinics

  Fellowship Hospital

• University Of Nebraska Medical Center

  Internship Hospital, 1986

• Movement Disorder Society, Member

• Florida Medical Association, Member

• Research Committee - Mayo Clinic Florida Committees, Member

• American Clinical Neurophysiology Society, Member

• Duval County Medical Society, Member

• Foundation of Parkinsonism and Related Disorders - World Federation of Neurology, Treasurer

• Japanese Society of Neurology, Member

• American Association of Neuromuscular and Electrodiagnostic Medicine, Fellow

• Smith Fellowship Program Reward Committee - Mayo Clinic Florida Committees, Member

• Finance Committee - International Society for Frontotemporal Dementias, Member

• Academic Appointments and Promotions Committee - Department of Neurology, Member

• Mayo Clinic Alumni Association - Mayo Clinic College of Medicine and Science - Department of Education Administration, Member

• American Neurological Association, Member

• Polish Neurological Society, Honorary Member

• Research Committee - Department of Neurology, Member

• Southeast Parkinson Disease Association Inc. Chapter of the National Parkinson Foundation serving the Central and Northern Florida areas, Member

• American Academy of Neurology, Member

• Outpatient Service - Mayo Clinic Florida Committees, Member

• Diagnostic Criteria for Adult-onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia Due toCSF1Rmutation, 2017-10-19

• Analysis of theC9orf72repeat in Parkinson's disease, essential tremor and restless legs syndrome, 2012-10-18

• Autosomal dominant cerebellar ataxia type III: a review of the phenotypic and genotypic characteristics, 2013-01-18

• Genotype-phenotype correlations in THAP1 dystonia: molecular foundations and description of new cases, 2012-02-28

• Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications, 2012-04-11

• The limbic and neocortical contribution of a-synuclein, tau and ß-amyloid to disease duration in dementia with Lewy bodies, 2017-10-31

• Neuropathologic basis of frontotemporal dementia in progressive supranuclear palsy Sakae et al, 2019-08-21

• Hypertrophic olivary degeneration: A clinico-radiologic study, 2016-04-12

• A clinicopathologic subtype of Alzheimer's disease presenting as corticobasal syndrome, 2019-08-06

• Microglial replacement therapy: a potential therapeutic strategy for incurableCSF1R-related leukoencephalopathy, 2020-12-07

• Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study, 2019-12-03

• Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated WithMAPT,GRN, andC9orf72Pathogenic Variants Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia, 2020-10-28

• Genetic modifiers in carriers of repeat expansions in theC9ORF72gene, 2014-09-20

• Validation of the Neuropathologic Criteria of the Third Consortium for Dementia with Lewy Bodies for Prospectively Diagnosed Cases, 2009-07-15

• DNAJC13 p.Asn855Ser mutation screening in Parkinson's disease and pathologically confirmed Lewy body disease patients, 2015-05-20

• Novel Mutations inTARDBP(TDP-43) in Patients with Familial Amyotrophic Lateral Sclerosis, 2008-09-19

• An evaluation of the impact ofMAPT,SNCAandAPOEon the burden of Alzheimer and Lewy body pathology, 2012-01-30

• Trajectory of Lobar Atrophy in Asymptomatic and SymptomaticGRNMutation Carriers: a Longitudinal MRI Study, 2019-12-12

• Partial Loss of Function of CSF1R in a Patient with White Matter Abnormalities, 2018-04-03

• Familial idiopathic basal ganglia calcification: a challenging clinical-pathological correlation, 2009-03-01

• Inhibition of colony stimulating factor-1 receptor (CSF-1R) as a potential therapeutic strategy for neurodegenerative diseases: opportunities and challenges, 2022-04-02

• Neuropsychological profile of CSF1R-related leukoencephalopathy, 2023-06-02

• Whole-exome sequencing for variant discovery in blepharospasm, 2018-05-16

• Genetic architecture of Parkinson's disease subtypes - Review of the literature, 2022-10-20

• Autosomal dominant Parkinson's disease caused bySNCAduplications, 2015-09-03

• Genetic variation of the retromer subunits VPS26A/B-VPS29 in Parkinson's disease, 2014-03-05

• Identification of common variants influencing risk of the tauopathy Progressive Supranuclear Palsy, 2011-06-19

• Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy, 2015-06-16

• SLC1A2rs3764087 does not associate with essential tremor, 2013-10-16

• Adult-onset leukodystrophies: a practical guide, recent treatment updates, and future directions, 2023-07-26

• Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion inC9ORF72, 2011-11-15

• Novel A18T and pA29S substitutions in a-synuclein may be associated with sporadic Parkinson's disease, 2013-08-02

• Independent and joint effects of theMAPTandSNCAgenes in Parkinson's disease, 2011-03-09

• Anatomy of Disturbed Sleep in Pallido-Ponto-Nigral Degeneration, 2014-01-21

• Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture, 2021-02-15

• Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3, 2020-10-21

• Cerebellar glutamatergic system impacts spontaneous motor recovery by regulatingGria1expression, 2022-09-05

• Association ofABI3andPLCG2missense variants with disease risk and neuropathology in Lewy body disease and progressive supranuclear palsy, 2020-10-22

• Phactr2and Parkinson's disease, 2009-02-10

• Analysis of Nuclear Export Sequence Regions of FUS-Related RNA-Binding Proteins in Essential Tremor, 2014-11-06

• Miro1 Marks Parkinson's Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson's Models., 2019-09-26

• Tau and neurofilament light-chain as fluid biomarkers in spinocerebellar ataxia type 3 GARCIA-MORENO et al., 2022-05-26

• Exonic Re-Sequencing of the Chromosome 2q24.3 Parkinson's Disease Locus, 2015-06-19

• Mutations in the colony stimulating factor 1 receptor (CSF1R) cause hereditary diffuse leukoencephalopathy with spheroids, 2011-12-25

• MAPThaplotype diversity in multiple system atrophy, 2016-06-16

• ABI3andPLCG2missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans, 2018-10-11

• An African-American Family with Dystonia, 2011-05-20

• Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease, 2014-04-10

• Cerebral Peduncle Angle: Unreliable in Differentiating Progressive Supranuclear Palsy From Other Neurodegenerative Diseases, 2016-08-11

• Clinicopathologic heterogeneity in FTDP-17 due to MAPT p.P301L mutation, including a patient with globular glial tauopathy, 2017-03-08

• Sequence variants in eukaryotic translation initiation factor 4-gamma (eIF4G1) are associated with Lewy body dementia, 2012-11-04

• Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent Hou et al., 2023-05-31

• Cognitive impairment in progressive supranuclear palsy is associated with tau burden, 2017-10-30

• Angiogenin variation and Parkinson's disease, 2012-03-23

• Slowly progressive dementia caused by MAPT R406W mutations: longitudinal report on a new kindred and systematic review, 2018-01-09

• TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease, 2013-06-21

• Profile of cognitive impairment and underlying pathology in multiple system atrophy, 2016-11-15

• InvestigatingELOVL7coding variants in Multiple System Atrophy, 2021-02-15

• Urine levels of the polyglutamine ataxin-3 protein are elevated in patients with spinocerebellar ataxia type 3, 2021-07-17

• Agraphia in patients with frontotemporal dementia and parkinsonism linked to chromosome 17 with P301L MAPT mutation: dysexecutive, aphasic, apraxic or spatial phenomenon?, 2012-11-05

• Multiple system atrophy and apolipoprotein E, 2018-02-14

• Author Correction: APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids, 2021-05-05

• Screening non-MAPTgenes of the Chr17q21 H1 haplotype in Parkinson's disease, 2020-08-01

• Cathepsin B p.Gly284Val Variant in Parkinson's Disease Pathogenesis, 2022-06-25

• Mitochondrial genomic variation in dementia with Lewy bodies: association with disease risk and neuropathological measures, 2022-07-14

• DRD3Ser9Gly andHS1BP3Ala265Gly are not associated with Parkinson Disease, 2009-06-12

• Genome-wide analyses as part of the international FTLD-TDP whole genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD, 2019-02-09

• Familial Parkinsonism: Study of Original Sagamihara PARK8 (I2020T) Kindred With Variable Clinicopathologic Outcomes, 2008-09-18

• APOEe2 is associated with increased tau pathology in primary tauopathy, 2018-10-22

• Length of normal alleles ofC9ORF72GGGGCC repeat do not influence disease phenotype, 2012-07-26

• Expanded GGGGCC hexanucleotide repeat in non-coding region ofC9ORF72causes chromosome 9p-linked frontotemporal dementia and amyotrophic lateral sclerosis, 2011-09-21

• Plasma neurofilament light predicts mortality in patients with stroke, 2020-11-11

• An adult-onset leukoencephalopathy with axonal spheroids and pigmented glia accompanied by brain calcifications A case report and a literature review of brain calcifications disorders, 2013-09-14

• High-throughput mutational analysis ofTOR1Ain primary dystonia, 2009-03-11

• LINGO1andLINGO2variants are associated with essential tremor and Parkinson disease, 2010-04-06

• Frontotemporal dementia and parkinsonism linked to chromosome 17 - the first Polish family, 2010-05-27

• Analysis ofCOQ2gene in multiple system atrophy, 2014-11-05

• Crohn's and Parkinson's Disease-Associated LRRK2 Mutations Alter Type II Interferon Responses in Human CD14+Blood Monocytes Ex Vivo, 2020-03-16

• DIAGNOSIS AND MANAGEMENT OF MARCHIAFAVA-BIGNAMI DISEASE: A REVIEW OF CT/MRI CONFIRMED CASES, 2013-08-26

• Deep brain stimulation for levodopa-refractory benign tremulous parkinsonism, 2016-06-24

• LRRK2 exonic variants and susceptibility to Parkinson's disease, 2011-08-30

• Hematopoietic Stem Cell Transplantation inCSF1R-Related Leukoencephalopathy: Retrospective Study on Predictors of Outcomes, 2022-12-12

• Fine-mapping of the non-coding variation driving the CaucasianLRRK2GWAS signal in Parkinson's disease, 2021-01-11

• Elucidating the genetics and pathology of Perry syndrome, 2009-09-04

• Genetic variants associated with myocardial infarction in thePSMA6gene and Chr9p21 are also associated with ischemic stroke, 2012-08-06

• The c.-237_236GA>TTTHAP1Sequence Variant Does Not Increase Risk for Primary Dystonia, 2011-03-02

• Daytime sleepiness in dementia with Lewy bodies is associated with neuronal depletion of the nucleus basalis of Meynert, 2018-02-03

• Association of Mitochondrial Genomic Background with Risk of Multiple System Atrophy, 2020-10-29

• Reply to: SNCA Variants Are Associated With Increased Risk of Multiple System Atrophy, 2016-01-16

• The AD tau core spontaneously self-assembles and recruits full-length tau to filaments, 2021-03-16

• Adult-Onset Leg Dystonia Due to a Missense Mutation inTHAP1, 2010-07-15

• Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy, 2022-08-23

• Frequency of Mutations inPRKN,PINK1, andDJ1in Patients With Early-Onset Parkinson Disease From Neighboring Countries in Central Europea, 2021-04-02

• Meta-analysis of Parkinson disease: Identification of a novel locus,RIT2, 2011-12-02

• Genetic screening and functional characterization ofPDGFRBmutations associated with Basal Ganglia Calcification of Unknown Etiology, 2014-06-03

• Latent trait modeling of tau neuropathology in progressive supranuclear palsy, 2021-02-26

• Ataxin-2 as potential disease modifier inC9ORF72expansion carriers, 2014-05-02

• Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19, 2021-07-14

• Whole-exome sequencing as a diagnostic tool in a family with episodic ataxia type 1, 2015-02-03

• A novel tau mutation, p.K317N, causes globular glial tauopathy, 2015-04-22

• Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), 2006-08-09

• Apolipoprotein E regulates lipid metabolism and a-synuclein pathology in human iPSC-derived cerebral organoids, 2021-08-28

• Profilin-1 mutations are rare in patients with amyotrophic lateral sclerosis and frontotemporal dementia, 2013-05-02

• InvestigatingFUSvariation in Parkinson's disease, 2016-01-15

• FTDP-17 WITH PICK BODY-LIKE INCLUSIONS ASSOCIATED WITH A NOVEL TAU MUTATION, p.E372G, 2016-10-05

• Evaluation of gastric emptying in familial and sporadic Parkinson disease?, 2009-05-17

• Novel mutation inMAPTexon 13 (p.N410H) causes corticobasal degeneration, 2013-11-19

• TAU AND NEUROFILAMENT LIGHT-CHAIN AS FLUID BIOMARKERS IN SPINOCEREBELLAR ATAXIA TYPE 3, 2022-05-26

• Distribution and characteristics of TDP-43 pathology in progressive supranuclear palsy, 2016-12-23

• APOE4exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids, 2020-11-02

• Association ofMAPTsubhaplotypes with clinical and demographic features in Parkinson's disease A.B. Deutschlanderet al., 2020-08-07

• Alpha-synuclein REP1 variants and survival in Parkinson's disease, 2014-02-27

• Correction to: A nonsynonymous mutation inPLCG2reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity, 2020-01-18

• Glucocerebrosidase mutations in diffuse Lewy body disease, 2016-01-16

• Diagnostic value of brain calcifications in Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia, 2016-09-15

• Evidence of cerebellar TDP-43 loss of function in FTLD-TDP, 2022-07-25

• Tau mutations as a novel risk factor for cancer - Letter Cancer and MAPT mutations - Letter, 2018-10-29

• Cognitive Profile ofLRRK2-related Parkinson's Disease, 2015-02-04

• Human leukocyte antigen variation and Parkinson's disease, 2011-04-11

• Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal dementia and GRN mutations: a genome-wide association study, 2018-04-30

• A mutant methionyl-tRNA synthetase-based toolkit to assess induced-mesenchymal stromal cell secretome in mixed-culture disease models, 2023-10-05

• LINGO1rs9652490 is associated with Essential Tremor and Parkinson Disease, 2009-08-31

• Pallidonigral TDP-43 pathology in Perry syndrome, 2008-08-23

• Clinical, pathological and genetic characteristics of Perry disease - new cases and literature review, 2021-08-26

• Substitution of PINK1 Gly411 modulates substrate receptivity and turnover AUTOPHAGY, 2022-12-05

• DJ-1 and aSYN in LRRK2 CSF do not correlate with striatal dopaminergic function, 2011-10-21

• Three sib-pairs of autopsy-confirmed progressive supranuclear palsy, 2014-11-15

• Loss of ability to work and ability to live independently in Parkinson's Disease, 2011-10-04

• Neuropathology of progressive supranuclear palsy after treatment with tilavonemab, 2022-08-27

• Parkinsonian features in hereditary diffuse leukoencephalopathy with spheroids (HDLS) andCSF1Rmutations, 2013-06-17

• Diagnosis and Treatment of Common Forms of Tremor, 2011-02-14

• Pathogenicity of exonic indels infused in sarcomain amyotrophic lateral sclerosis, 2010-11-12

• Is Pre-Symptomatic Immunosuppression Protective inCSF1R-Related Leukoencephalopathy?, 2021-02-15

• A nonsynonymous mutation inPLCG2reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity, 2019-05-26

• Identification and functional characterization of novel mutations including frameshift mutation in exon 4 ofCSF1Rin patients with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia, 2018-08-22

• LRRTM3 Interacts with APP and BACE1 and Has Variants Associating with Late-Onset Alzheimer's Disease (LOAD), 2013-06-04

• Rare variants inMC1R/TUBB3exon 1 are not associated with Parkinson's disease, 2016-01-19

• Early-Onset Parkinson Disease Screening in Patients From Nigeria, 2021-01-14

• DCTN1-related neurodegeneration: Perry syndrome and beyond, 2017-06-12

• DCTN1mutations in Perry syndrome, 2009-01-11

• Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia: Review of Clinical Manifestations as Foundations for Therapeutic Development, 2022-02-03

• Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples AUTOPHAGY, 2020-10-28

• Genetic disorders with tau pathology: a review of the literature and report of two patients with tauopathy and positive family histories, 2015-11-10

• Genetic variation ofOmi/HtrA2and Parkinson's disease, 2008-09-14

• First neuropathological description of a patient with Parkinson's disease and LRRK2 p.N1437H mutation, 2011-12-06

• A Swedish family withde novoa-synuclein A53T mutation: Evidence for early cortical dysfunction, 2009-07-25

• Tremor in progressive supranuclear palsy, 2016-03-22

• APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia: Implications for therapeutic strategy, 2021-09-29

• Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS): a misdiagnosed disease entity, 2011-11-01

• MAPTsubhaplotypes in corticobasal degeneration: assessing associations with disease risk, severity of tau pathology, and clinical features, 2020-12-07

• Evaluation of the Role ofSNCAVariants in Survival without Neurological Disease, 2012-08-13

• A familial form of parkinsonism, dementia, and motor neuron disease: a longitudinal study, 2014-08-19

• Brain MR spectroscopy changes precede frontotemporal lobar degeneration phenoconversion inMAPTmutation carriers, 2019-06-07

• Serotonin transporter binding and motor onset of Parkinson's disease in asymptomaticLRRK2mutation carriers: a cross-sectional study, 2017-03-20

• The protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent ofMAPTandSNCAvariants, 2013-08-17

• TMEM106BprotectsC9ORF72expansion carriers against frontotemporal dementia, 2014-01-03

• Update on novel familial forms of Parkinson's disease and multiple system atrophy, 2014-10-07

• Investigating the role ofFUSexonic variants in Essential Tremor, 2013-04-16

• A Mutant Methionyl-tRNA Synthetase-Based toolkit to assess induced-Mesenchymal Stromal Cell secretome in mixed-culture disease models, 2023-05-03

• Replication of progressive supranuclear palsy genome-wide association study identifiesSLCO1A2andDUSP10as new susceptibility loci, 2018-07-09

• Prevalence of GBA p.K198E mutation in Colombian and Hispanic populations, 2020-03-12

• Latin America's first case of Perry syndrome and a new treatment option for respiratory insufficiency, 2014-02-06

• A Novel Tau Mutation in Exon 12, p.Q336H, Causes Hereditary Pick Disease, 2015-08-13

• Association of Essential Tremor With Novel Risk Loci A Genome-Wide Association Study and Meta-analysis Association of Essential Tremor With Novel Risk Loci, 2022-01-04

• Association of Parkinson disease age of onset withDRD2,DRD3andGRIN2Bpolymorphisms, 2015-11-25

• Associations of mitochondrial genomic variation with corticobasal degeneration, progressive supranuclear palsy, and neuropathological tau measures, 2020-09-17

• Cancer in Parkinson's disease, 2016-06-20

• Autosomal dominant cerebellar ataxia type I: A review of the phenotypic and genotypic characteristics, 2011-05-28

• Occurrence of Crohn's disease with Parkinson's disease, 2017-02-10

• LRRK2variation and dementia with Lewy bodies, 2016-07-29

• De Novo TruncatingFUSGene Mutation as a Cause of Sporadic Amyotrophic Lateral Sclerosis, 2010-08-04

• Three families with Perry syndrome from distinct parts of the world, 2014-05-13

• RAB39Bgene mutations are not a common cause of Parkinson's disease or dementia with Lewy bodies, 2016-03-24

• Study ofLRRK2variation in tauopathy: progressive supranuclear palsy and corticobasal degeneration, 2016-10-06

• Phosphorylated a-synuclein in Parkinson's disease: correlation depends on disease severity, 2015-01-31

• TREM2 R47H variant and risk of essential tremor: A cross-sectional international multicenter study, 2014-12-24

• The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity, 2017-04-24

• TARDBPmutations in Parkinson's disease, 2012-12-08

• MAPThaplotype H1G is associated with increased risk of dementia with Lewy bodies, 2016-06-07

• FGF20and Parkinson's disease: No evidence of association or pathogenicity via a-synuclein expression, 2009-02-15

• Clinical presentation of a patient withSLC20A2andTHAP1deletions: differential diagnosis of oromandibular dystonia, 2015-01-08

• Brain abnormalities, neurodegeneration, and dysosteosclerosis (BANDDOS): new cases, systematic literature review, and associations with CSF1R-ALSP, 2023-06-22

• Genetics of Parkinson disease and essential tremor, 2014-01-24

• DCTN1mutation analysis in families with progressive supranuclear palsy-like phenotype, 2014-09-13

• No evidence forDNM3as genetic modifier of age at onset in idiopathic Parkinson's disease, 2018-09-22

• Genetic characterization of Parkinson's disease patients in Ecuador and Colombia, 2020-05-15

• Brain atrophy over time in genetic and sporadic frontotemporal dementia: a study on 198 serial MRI, 2015-02-12

• Cerebellar ataxia in progressive supranuclear palsy: an autopsy study of PSP-C, 2016-02-03

• GCH1expression in human cerebellum from healthy individuals is not gender dependant, 2009-06-30

• Frequency of spinocerebellar ataxia mutations in patients with multiple system atrophy, 2021-01-27

• Poly (ADP-Ribose) and a-synuclein extracellular vesicles in patients with Parkinson disease: A possible biomarker of disease severity, 2022-04-08