Dr. Vernon Sondak, MD

• General Surgery

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• University Of California-los Angeles

  Fellowship Hospital, 1984

• Ronald Reagan Ucla Medical Center

  Internship Hospital, 1981

• Boston University Chobanian & Avedisian School Of Medicine

  Medical School, 1980

• Single cell characterization of the cellular landscape of acral melanoma identifies novel targets for immunotherapy, 2022-05-13

• The State of Melanoma: Emergent Challenges and Opportunities, 2021-01-07

• Case-Control Study of Cutaneous Human Papillomaviruses in Squamous Cell Carcinoma of the Skin, 2012-06-15

• Combined BRAF and HSP90 inhibition in patients with unresectableBRAFV600E mutant melanoma, 2018-04-19

• Phase II Trial of Sorafenib in Combination with Carboplatin and Paclitaxel in Patients with Metastatic Uveal Melanoma: SWOG S0512, 2012-11-30

• The association ofMUC16mutation with tumor mutation burden and its prognostic implications in cutaneous melanoma, 2020-07-01

• Single institution outcome experience using AlloDerm® as temporary coverage or definitive reconstruction for cutaneous and soft tissue malignancy defects, 2015-07-14

• International Center-Level Variation in Utilization of Completion Lymph Node Dissection and Adjuvant Systemic Therapy for Sentinel Lymph Node Positive Melanoma, 2022-01-27

• Treatment of Head and Neck Melanoma in Situ with Staged Contoured Marginal Excisions, 2016-10-27

• Metastasectomy for distant metastatic melanoma: Analysis of data from the first Multicenter Selective Lymphadenectomy Trial (MSLT-I), 2012-05-31

• Resection Margins in Merkel Cell Carcinoma: Is a 1-cm Margin Wide Enough?, 2018-08-02

• The "Great Debate” at Melanoma Bridge 2020: December, 5th, 2020, 2021-04-07

• A Collision of Diseases: Chronic Lymphocytic Leukemia Discovered During Lymph Node Biopsy for Melanoma, 2012-11-20

• Pediatric Melanoma: Analysis of an International Registry, 2013-09-10

• Surveillance of sentinel node positive melanoma patients who receive adjuvant therapy without undergoing completion lymph node dissection, 2021-08-06

• Improved survival of patients with melanoma brain metastases in the era of targeted BRAF and immune checkpoint therapies, 2017-10-12

• Gene variants in angiogenesis and lymphangiogenesis and cutaneous melanoma progression, 2013-03-05

• Activity-based protein profiling shows heterogeneous signaling adaptations to BRAF inhibition, 2016-11-17

• A Phase II Trial of Complete Resection for Stage IV Melanoma: Results of Southwest Oncology Group (SWOG) Clinical Trial S9430, 2011-03-31

• Viruses in Skin Cancer (VIRUSCAN): Study design and baseline characteristics of a prospective clinic-based cohort study, 2019-08-19

• Neoadjuvant BRAF-targeted therapy in regionally advanced and oligometastatic melanoma, 2019-09-12

• Regional Radiation Therapy Impacts Outcome for Node-Positive Cutaneous Melanoma, 2020-12-19

• Inactivation of RASA1 promotes melanoma tumorigenesis via R-Ras activation, 2016-03-16

• Brief Communication: Efficacy of Adoptive Cell Transfer of Tumor Infiltrating Lymphocytes after Lymphopenia Induction for Metastatic Melanoma, 2015-06-11

• Comparison of Single-Photon Emission Computed Tomography -Computed Tomography (SPECT/CT) and Conventional Planar Lymphoscintigraphy for Sentinel Node Localization in Patients with Cutaneous Malignancies, 2016-09-22

• Clinical Characteristics and Outcomes for Solitary Fibrous Tumor (SFT): A Single Center Experience, 2015-10-15

• Progression of cutaneous melanoma: implications for treatment, 2012-08-15

• Randomized Phase II Trial of Sorafenib with Temsirolimus or Tipifarnib in Untreated Metastatic Melanoma (S0438), 2012-01-06

• Clinicopathologic Predictors of Survival in Patients with Desmoplastic Melanoma, 2015-03-26

• Expression of CXCR4, E-Cadherin, Bcl-2, and Survivin in Merkel Cell Carcinoma: An Immunohistochemical Study Using a Tissue Microarray, 2015-10-01

• Behavior of Cutaneous Adnexal Malignancies: A Single Institution Experience, 2018-06-14

• Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: Analysis of 5,823 cases as the basis of the first consensus staging system for this cancer, 2010-06-19

• Both Tumor Depth and Diameter Are Predictive of Sentinel Lymph Node Status and Survival in Merkel Cell Carcinoma, 2015-06-02

• Enhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to males, 2022-06-03

• Active Surveillance of Patients Who Have Sentinel Node Positive Melanoma: An International, Multi-Institution Evaluation of Adoption and Early Outcomes After the Multicenter Selective Lymphadenectomy Trial II (MSLT-2), 2021-04-07

• Management of Sentinel Lymph Node Metastasis in Merkel Cell Carcinoma: Completion Lymphadenectomy, Radiation, or Both?, 2018-10-11

• Case-Control Study of Cutaneous Human Papillomavirus Infection in Basal Cell Carcinoma of the Skin, 2013-01-10

• Conjunctival Melanomas Harbor BRAF and NRAS Mutations-Letter, 2013-10-28

• Sentinel Lymph Node Biopsy Is Indicated for Patients With Thick Clinically Lymph Node-Negative Melanoma, 2015-02-11

• Robotic-assisted Trans-peritoneal Pelvic Lymphadenectomy For Metastatic Melanoma: Early Outcomes Compared To Open Pelvic Lymphadenectomy, 2016-01-14

• Nonsurgical Treatment Options for Basal Cell Carcinoma, 2011-01-09

• High frequency of brain metastases after adjuvant therapy for high-risk melanoma, 2017-10-10

• Sentinel node biopsy is indicated for thin melanomas =0.76 mm, 2012-07-06

• Cutaneous human papillomaviruses and the risk of keratinocyte carcinomas, 2021-07-15

• Melanoma Staging: Evidence-Based Changes in the American Joint Committee on Cancer Eighth Edition Cancer Staging Manual, 2017-10-13

• Combined Analysis of Phase III Trials Evaluating [99mTc]Tilmanocept and Vital Blue Dye for Identification of Sentinel Lymph Nodes in Clinically Node-Negative Cutaneous Melanoma, 2012-10-03

• Adjuvant pembrolizumab versus interferon alfa-2b or ipilimumab in resected high-risk melanoma, 2022-03-01

• Granulomatous and Sarcoid-like Immune-Related Adverse Events following CTLA4 and PD1 Blockade Adjuvant Therapy of Melanoma: A Combined Analysis of ECOG-ACRIN E1609 and SWOG S1404 Phase III Trials and a Literature Review, 2023-04-29

• Paradoxical oncogenesis and the long term consequences of BRAF inhibition in melanoma, 2013-05-28

• Synthesis and Characterization of a Melanoma-Targeted Fluorescence Imaging Probe by Conjugation of a Melanocortin 1 Receptor (MC1R) Specific Ligand, 2012-11-27

• Adjuvant Vaccine Immunotherapy of Resected, Clinically Node-negative Melanoma: Long-Term Outcome and Impact of HLA Class I Antigen Expression on Overall Survival, 2014-07-03

• The heat shock protein-90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms, 2012-02-20

• Cutaneous Human Papillomavirus Infection and Development of Subsequent Squamous Cell Carcinoma of the Skin, 2016-11-07

• A Brief History of Melanoma: From Mummies to Mutations, 2012-03-06

• Fibronectin induction abrogates the BRAF inhibitor response ofBRAFV600E/PTEN-null melanoma cells, 2015-06-15

• Inhibition of autophagy enhances the effects of the AKT inhibitor MK-2206 when combined with paclitaxel and carboplatin inBRAFwild-type melanoma, 2014-02-21

• A Phase II Study of RO4929097 Gamma-Secretase Inhibitor in Metastatic Melanoma: SWOG 0933, 2014-09-23

• Case-control Study of Merkel Cell Polyomavirus Infection and Cutaneous Squamous Cell Carcinoma, 2011-10-20

• Association between human polyomaviruses and keratinocyte carcinomas: A prospective cohort study, 2021-06-29

• Phase II Trial of Combination Thalidomide plus Temozolomide in Patients with Metastatic Malignant Melanoma: Southwest Oncology Group S0508, 2010-01-15

• Ceritinib enhances the efficacy of trametinib inBRAF/NRAS-wild type melanoma cell lines, 2017-11-13

• Combination Nivolumab, CD137 Agonism, and Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes for Patients with Metastatic Melanoma, 2022-12-15

• Telomere length and risk of melanoma, squamous cell carcinoma, and basal cell carcinoma, 2013-03-21

• A Randomized Phase II Trial of Combined Nivolumab and Ipilimumab with or without Stereotactic Body Radiation Therapy for Advanced Merkel Cell Carcinoma, 2022-09-12

• Higher than reported adolescent and young adult clinical trial enrollment during the "Golden Age” of melanoma clinical trials, 2018-02-25

• Inhibition of HSP90 by AT13387 Delays the Emergence of Resistance to BRAF Inhibitors and Overcomes Resistance to dual BRAF and MEK Inhibition in Melanoma Models, 2014-10-27

• Desmoplastic Melanoma: Is There a Role for Sentinel Lymph Node Biopsy?, 2013-02-07

• An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: version 2.0, 2018-05-30

• Evaluation of the Indications for Sentinel Node Biopsy in Early-Stage Melanoma with the Advent of Adjuvant Systemic Therapy: An International, Multicenter Study, 2022-05-13

• Patterns and timing of sunlight exposure and risk of basal cell and squamous cell carcinomas of the skin - a case-control study, 2012-09-20

• New challenges in endpoints for drug development in advanced melanoma, 2011-12-05

• Radiotherapy Influences Local Control in Patients With Desmoplastic Melanoma, 2013-10-18

• Single cell characterization of the immune microenvironment of melanoma brain and leptomeningeal metastases, 2021-05-25

• The Unique Clinical Characteristics of Melanoma Diagnosed in Children, 2012-08-03

• HDAC8 regulates a stress response pathway in melanoma to mediate escape from BRAF inhibitor therapy, 2019-04-15

• XL888 limits vemurafenib-induced proliferative skin events by suppressing paradoxical MAPK activation, 2015-06-03

• Stratifying SLN incidence in intermediate thickness melanoma patients, 2017-12-14

• Combination of Ipilimumab and Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes for Patients with Metastatic Melanoma, 2018-03-02

• Merkel cell polyomavirus (MCV) T-antigen seroreactivity, MCV DNA in eyebrow hairs, and squamous cell carcinoma, 2015-10-19

• A Phase II Trial of Imatinib Mesylate in Merkel Cell Carcinoma (Neuroendocrine Carcinoma of the Skin): A Southwest Oncology Group Study (S0331), 2010-10-14

• Case-control study of genus-beta human papillomaviruses in plucked eyebrow hairs and cutaneous squamous cell carcinoma, 2013-11-12

• Merkel Cell Carcinoma of Unknown Primary Origin, 2012-01-21

• The Genomic Landscape of Merkel Cell Carcinoma and Clinicogenomic Biomarkers of Response to Immune Checkpoint Inhibitor Therapy, 2019-08-09

• Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities, 2019-02-19

• Combination Therapies for Melanoma: A New Standard of Care?, 2016-02-22

• Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities, 2022-09-01

• Is a Wider Margin (2 cm vs. 1 cm) for a 1.01-2.0 mm Melanoma Necessary?, 2016-03-08

• Cutaneous Leiomyosarcoma: A Single Institution Experience of Treatment and Outcomes with a Standardized Margin of Resection, 2015-07-12

• In vivoandin silicopharmacokinetics and biodistribution of a melanocortin receptor 1 targeted agent in preclinical models of melanoma, 2013-07-08

• PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression, 2011-02-11

• Ligand independent EphA2 signaling drives the adoption of a targeted therapy-mediated metastatic melanoma phenotype, 2014-12-26

• Inhibition of Wee1, AKT and CDK4 underlies the efficacy of the HSP90 inhibitor XL888 in anin vivomodel ofNRASmutant melanoma, 2013-03-28