Dr. Robert Pignolo, MD

• Geriatric Medicine

• Internal Medicine

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• Drexel University

  Medical School, 2016

• Targeted clearance ofp21- but notp16-positive senescent cells prevents radiation-induced osteoporosis and increased marrow adiposity, 2022-04-01

• Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease' EBioMedicine 47 (2019) 446-456, 2020-01-23

• Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole-Exome Sequencing in a Patient with Delayed-Onset Fibrodysplasia Ossificans Progressiva (FOP) UsingACVR1R206H-Specific Human Cellular and Zebrafish Models, 2022-11-15

• Palovarotene for Fibrodysplasia Ossificans Progressiva ( FOP ): Results of a Randomized, Placebo-Controlled, Double-Blind Phase 2 Trial Pignolo et al., 2022-08-17

• Retinoid Agonists in the Targeting of Heterotopic Ossification, 2021-11-19

• Adherence to Public Health Measures Mitigates Risk of COVID-19 Infection in Older Adults: A Community-based Study, 2020-12-28

• Pharmacologic Interventions for Fracture Risk Reduction in the Oldest Old: What Is the Evidence? Sfeir and Pignolo, 2021-09-05

• Rural-urban health disparities for mood disorders and obesity in a midwestern community, 2020-10-01

• In vitroandin vivoeffects of zoledronic acid on senescence and senescence-associated secretory phenotype markers, 2023-05-07

• Current challenges and opportunities in the care of patients with fibrodysplasia ossificans progressiva (FOP): an international, multi-stakeholder perspective, 2022-04-18

• Bone Aging, Cellular Senescence, and Osteoporosis Pignolo et al., 2021-04-02

• Predicting delirium risk using an automated "Mayo Delirium Prediction” tool - Development and Validation of a risk stratification model, 2021-02-10

• Do the telomere ends justify the physical means?, 2021-09-17

• A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues, 2022-08-16

• Fisetin for COVID-19 in Skilled Nursing Facilities (COVID-FIS): Senolytic Trials in the COVID Era, 2021-08-20

• Whole-body Computed Tomography Versus Dual Energy X-ray Absorptiometry for Assessing Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva, 2021-07-31

• Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease, 2019-09-18

• Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span, 2020-09-30

• Garetosmab in fibrodysplasia ossificans progressiva: a randomized, double-blind, placebo-controlled phase 2 trial, 2023-09-28

• Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop, 2021-11-10

• Patients with ACVR1R206Hmutations have an increased prevalence of cardiac conduction abnormalities on electrocardiogram in a natural history study of Fibrodysplasia Ossificans Progressiva, 2020-07-29

• Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes, 2019-05-03

• Correction to: Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes, 2019-05-23