Dr. Leslie Grammer, MD

• Allergy & Immunology

• Internal Medicine

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Mcgaw Medical Center Of Northwestern University

  Fellowship Hospital, 1981

• Mcgaw Medical Center Of Northwestern University

  Residency Hospital, 1979

• Northwestern Memorial Hospital|northwestern University Feinberg School Of Medicine

  Internship Hospital, 1977

• Northwestern University Feinberg School Of Medicine

  Medical School, 1976

• Group 2 innate lymphoid cells are elevated and activated in chronic rhinosinusitis with nasal polyps J. A. Poposkiet al., 2017-04-19

• Suppressor of cytokine signaling 3 expression is diminished in sinonasal tissues from patients with chronic rhinosinusitis with nasal polyps, 2013-09-29

• Chronic rhinosinusitis with nasal polyps is characterized by B-cell inflammation and EBV-induced protein 2 expression, 2013-03-06

• Integrin ß6 microparticles in nasal lavage fluids; potential new biomarkers for basal cell activation in chronic rhinosinusitis, 2020-08-17

• Proton pump inhibitors decrease eotaxin-3/CCL26 expression in chronic rhinosinusitis with nasal polyps: the possible role of the non-gastric H,K-ATPase, 2016-10-04

• Chronic Airway Inflammation Provides a Unique Environment for B Cell Activation and Antibody Production, 2017-01-26

• The burden of asthma in the Chicago community fifteen years after the availability of national asthma guidelines: The design and initial results from the CHIRAH study?, 2009-01-23

• Substance P downregulates expression of the high affinity IgE receptor (FceRI) by human mast cells, 2010-02-01

• Glandular mast cells with distinct phenotype are highly elevated in chronic rhinosinusitis with nasal polyps, 2012-04-24

• Microparticles in nasal lavage fluids in chronic rhinosinusitis; potential biomarkers for diagnosis of Aspirin Exacerbated Respiratory Disease, 2017-02-24

• Association between severity of asthma and degree of chronic rhinosinusitis, 2012-06-21

• Atopic profile of patients failing medical therapy for chronic rhinosinusitis, 2011-03-30

• Evidence for altered levels of Immunoglobulin D in the nasal airway mucosa of patients with chronic rhinosinusitis, 2017-06-16

• Relationships between severity of chronic rhinosinusitis and nasal polyposis, asthma, and atopy, 2013-08-09

• Elevated expression of the chemokine CCL18 in chronic rhinosinusitis with nasal polyps, 2011-09-23

• Increased expression of the epithelial anion transporter Pendrin/SLC26A4 in nasal polyps of patients with Chronic Rhinosinusitis, 2015-07-02

• Associations between inflammatory endotypes and clinical presentations in chronic rhinosinusitis, 2019-05-22

• Responsiveness and Convergent Validity of a New Patient-Reported Outcome Measure for Chronic Rhinosinusitis (CRS-PRO), 2020-04-30

• Development and Preliminary Validation of a New Patient Reported Outcome Measure for Chronic Rhinosinusitis (CRS-PRO), 2020-05-04

• Neutrophils are a major source of the epithelial barrier disrupting cytokine Oncostatin M in mucosal airways disease, 2016-12-18

• The Clinical Significance of Specific Antibody Deficiency (SAD) Severity in Chronic Rhinosinusitis (CRS), 2017-01-26

• Role of RANK-L as a potential inducer of ILC2-mediated type 2 inflammation in chronic rhinosinusitis with nasal polyps, 2019-10-22

• Prevalence and characterization of chronic rhinosinusitis in patients with non-cystic fibrosis bronchiectasis at a tertiary care center in the United States, 2019-10-07

• EVIDENCE FOR ALTERED ACTIVITY OF THE IL-6 PATHWAY IN CHRONIC RHINOSINUSITIS WITH NASAL POLYPS, 2009-12-11

• Studies on activation and regulation of the coagulation cascade in chronic rhinosinusitis with nasal polyps, 2022-03-07

• TNF induces the production of type 2 cytokines in human group 2 innate lymphoid cells, 2019-09-14

• Mechanisms and biomarkers of inflammatory endotypes in chronic rhinosinusitis without nasal polyps, 2020-12-14

• Common Filaggrin null mutations are associated with atopy but not with chronic rhinosinusitis, 2015-03-04

• Antiphospholipid Antibodies are Elevated and Functionally Active in Chronic Rhinosinusitis with Nasal Polyps, 2022-03-14

• A prospective analysis evaluating tissue biopsy location and its clinical relevance in chronic rhinosinusitis with nasal polyps, 2017-09-01

• Perspectives on the etiology of chronic rhinosinusitis: An immune barrier hypothesis, 2008-09-10

• Obesity and Asthma Morbidity in a Community-Based Adult Cohort in a Large Urban Area: the Chicago Initiative to Raise Asthma Health Equity (CHIRAH), 2012-11-01

• Studies of the role of basophils in aspirin-exacerbated respiratory disease pathogenesis, 2021-04-02

• Evidence for intranasal anti-nuclear autoantibodies in Chronic Rhinosinusitis with Nasal Polyps., 2011-10-13

• Clinical Characteristics of Patients with Chronic Rhinosinusitis with Nasal Polyps, Asthma, and Aspirin Exacerbated Respiratory Disease, 2017-03-09

• Clinical Characteristics of Patients with Chronic Rhinosinusitis without Nasal Polyps in an Academic Setting, 2018-10-25

• Evaluating Metrics of Responsiveness Using Patient-Reported Outcome Measures in Chronic Rhinosinusitis, 2016-11-07

• Blockade of peanut allergy with a novel Ara h 2-Fc? fusion protein in mice, 2012-11-27

• Classical Complement Pathway Activation in the Nasal Tissue of Patients With Chronic Rhinosinusitis, 2016-12-12

• Heterogenous inflammatory patterns in chronic rhinosinusitis without nasal polyps in Chicago, Illinois, 2016-09-14

• IL-10, TGF-ß and glucocorticoid prevent the production of type 2 cytokines in human group 2 innate lymphoid cells, 2017-10-23

• Incidence and associated pre-morbid diagnoses of patients with chronic rhinosinusitis, 2013-03-28

• Characterization of specific antibody deficiency in adults with medically refractory chronic rhinosinusitis, 2012-06-21

• Activation of the 15-Lipoxygenase Pathway in Aspirin Exacerbated Respiratory Disease, 2020-05-01

• Increased thrombin activatable fibrinolysis inhibitor (TAFI) in chronic rhinosinusitis with nasal polyps, 2019-09-25

• Increased expression of factor XIII-A in patients with chronic rhinosinusitis with nasal polyps, 2013-03-28

• Clinical Characteristics of Adults with Chronic Rhinosinusitis and Specific Antibody Deficiency, 2014-11-25

• Basophils are elevated in nasal polyps of patients with chronic rhinosinusitis without aspirin sensitivity, 2014-03-15

• Reduced Expression of Antimicrobial PLUNC Proteins in Nasal Polyp Tissues of patients with Chronic Rhinosinusitis, 2012-05-11

• Epithelial activators of type 2 inflammation; elevation of TSLP, but not IL-25 or IL-33, in chronic rhinosinusitis with nasal polyps in Chicago, Illinois, 2018-07-26

• Elevation of activated neutrophils in chronic rhinosinusitis with nasal polyps, 2021-12-22

• Elevated expression of CC Chemokine ligand 23 in eosinophilic chronic rhinosinusitis with nasal polyps, 2011-04-17

• Clinical factors associated with acute exacerbations of chronic rhinosinusitis, 2020-01-29

• Increased non-eosinophilic nasal polyps in chronic rhinosinusitis in U.S. second-generation Asians suggests genetic regulation of eosinophilia, 2014-10-11

• Oncostatin M promotes mucosal epithelial barrier dysfunction and is elevated in eosinophilic mucosal disease, 2015-04-01

• Evidence for Diminished Levels of Epithelial Psoriasin and Calprotectin in Chronic Rhinosinusitis, 2010-01-07

• Regional differences in the expression of innate host defense molecules in sinonasal mucosa, 2013-07-26

• Age-related differences in the pathogenesis of chronic rhinosinusitis, 2012-01-10

• Tissue proteases convert CCL23 into potent monocyte chemoattractants in chronic rhinosinusitis, 2015-11-10

• Thymic stromal lymphopoietin activity is increased in nasal polyps of chronic rhinosinusitis, 2013-05-17

• Proprotein convertases generate a highly functional heterodimeric form of thymic stromal lymphopoietin in humans, 2016-10-12

• The Impact of Health Literacy and Socioeconomic Status on Asthma Disparities, 2012-01-25

• Elevated presence of myeloid dendritic cells in nasal polyps of patients with chronic rhinosinusitis, 2015-06-10