Dr. Eugene Koay, MD

• Radiation Oncology

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• Clinicopathological correlation of radiologic measurement of post-therapy tumor size and tumor volume for pancreatic ductal adenocarcinoma, 2020-11-14

• OncogenicKRASrecruits an expansive transcriptional network through mutant p53 to drive pancreatic cancer metastasis, 2021-04-10

• Regression of Stage IV Pancreatic Cancer to Curative Surgery and Introduction of a Novel Ex-Vivo Chemosensitivity Assay, 2015-12-21

• Proton beam therapy outcomes for localized unresectable hepatocellular carcinoma, 2019-01-16

• Dosimetric uncertainties resulting from interfractional anatomic variations for patients receiving pancreas stereotactic body radiation therapy and cone-beam CT image guidance, 2021-08-13

• Simultaneous Inhibition of Hedgehog Signaling and Tumor Proliferation Remodels Stroma and Enhances Pancreatic Cancer Therapy, 2018-01-09

• Comparative Analyses of the Clinicopathologic Features of Short-Term and Long-Term Survivors of Patients with Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant Therapy and Pancreatoduodenectomy, 2023-06-18

• Alliance for clinical trials in oncology (ALLIANCE) trial A021501: preoperative extended chemotherapy vs. chemotherapy plus hypofractionated radiation therapy for borderline resectable adenocarcinoma of the head of the pancreas, 2017-07-27

• Image-guided mathematical modeling for pharmacological evaluation of nanomaterials and monoclonal antibodies, 2020-04-21

• Severe Lymphopenia During Neoadjuvant Chemoradiation for Esophageal Cancer: A Propensity Matched Analysis of the Relative Risk of Proton versus Photon-Based Radiation Therapy, 2017-12-14

• A prospective parallel design study testing non-inferiority of customized oral stents made using 3D printing or manually fabricated methods, 2020-04-13

• Differential Association between Circulating Lymphocyte Populations with Outcome after Radiotherapy in Subtypes of Liver Cancer, 2018-04-17

• Dose-Escalated Radiation Therapy for Pancreatic Cancer: A Simultaneous Integrated Boost Approach, 2020-02-13

• Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma Exhibit Differential Growth and Metabolic Patterns in the Pre-Diagnostic Period: Implications for Early Detection, 2020-12-02

• Leveraging deep learning-based segmentation and contours-driven deformable registration for dose accumulation in abdominal structures, 2022-11-02

• Is the worst of the COVID-19 global pandemic yet to come? Application of financial mathematics as candidate predictive tools, 2021-05-20

• Intraductal Papillary Mucinous Neoplasms of the Pancreas: Current Understanding and Future Directions for Stratification of Malignancy Risk, 2018-01-27

• Dose escalation of radiotherapy in unresectable extrahepatic cholangiocarcinoma, 2018-08-27

• Magnetic Resonance Guided Radiation Therapy for Pancreatic Adenocarcinoma, Advantages, Challenges, Current Approaches, and Future Directions, 2021-05-11

• Outcomes and Toxicities of Modern Combined Modality Therapy with Atezolizumab Plus Bevacizumab and Radiation Therapy for Hepatocellular Carcinoma, 2022-04-09

• Ablative Liver Radiotherapy for Unresected Intrahepatic Cholangiocarcinoma: Patterns of Care and Survival in the United States, 2022-04-13

• Creating customized oral stents for head and neck radiotherapy using 3D scanning and printing, 2019-08-19

• Image Fusion Involving Real-Time Transabdominal or Endoscopic Ultrasound for Gastrointestinal Malignancies: Review of Current and Future Applications, 2022-12-19

• Development of a MicroRNA Signature Predictive of Recurrence and Survival in Pancreatic Ductal Adenocarcinoma, 2021-10-15

• Design and fabrication of a 3D-printed oral stent for head and neck radiotherapy from routine diagnostic imaging, 2017-11-16

• Mass Transport Model of Radiation Response: Calibration and Application to Chemoradiation for Pancreatic Cancer, 2022-05-26

• Analysis and prediction of liver volume change maps derived from computational tomography scans acquired pre- and post-radiation therapy, 2023-10-04

• Impact of Hypofractionated and Standard Fractionated Chemoradiation Prior to Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma, 2016-05-31

• SMAD4gene mutation renders pancreatic cancer resistance to radiotherapy through promotion of autophagy, 2018-03-30

• Theory and Experimental Validation of a Spatio-temporal Model of Chemotherapy Transport to Enhance Tumor Cell Kill, 2016-06-10

• Development of an Immune-Pathology Informed Radiomics Model for Non-Small Cell Lung Cancer, 2018-01-31

• Benchmarking Outcomes after Ablative Radiotherapy for Molecularly Characterized Intrahepatic Cholangiocarcinoma, 2021-12-01

• NATURAL HISTORY OF T1N0M0 HEPATOCELLULAR CARCINOMA: LARGE SCALE STUDY IN THE UNITED STATES, 2017-07-06

• Understanding Drug Resistance in Breast Cancer with Mathematical Oncology, 2014-04-02

• Local Therapy Reduces the Risk of Liver Failure and Improves Survival in Patients with Intrahepatic Cholangiocarcinoma: a Comprehensive Analysis of 362 Consecutive Patients, 2016-12-16

• Lung tumor segmentation methods: Impact on the uncertainty of radiomics features for non-small cell lung cancer, 2018-10-04

• Mechanistic Modeling Identifies Drug-Uptake History as Predictor of Tumor Drug Resistance and Nano-Carrier-Mediated Response, 2013-11-11

• The Gut Microbiome as a Biomarker and Therapeutic Target in Hepatocellular Carcinoma, 2023-10-07

• Novel Use of Low-Dose Radiotherapy to Modulate the Tumor Microenvironment of Liver Metastases, 2021-12-15

• Detection of vessel bifurcations in CT scans for automatic objective assessment of deformable image registration accuracy, 2021-08-25

• Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer, 2019-05-01

• CEA as a blood-based biomarker in anal cancer, 2021-05-25

• Cost-effectiveness of Consensus Guideline Based Management of Pancreatic Cysts: The Sensitivity and Specificity Required for Guidelines to be Cost-Effective, 2020-07-29

• Computed Tomography-Based Biomarker Outcomes in a Prospective Trial of Preoperative FOLFIRINOX and Chemoradiation for Borderline Resectable Pancreatic Cancer, 2019-08-23

• Gemcitabine enhances the transport of nanovector-albumin-bound paclitaxel in gemcitabine-resistant pancreatic ductal adenocarcinoma, 2017-07-04

• The Sequential Radiographic Effects of Preoperative Chemotherapy and (Chemo)Radiation on Tumor Anatomy in Patients with Localized Pancreatic Cancer, 2020-04-07

• Predictive Modeling for Voxel-Based Quantification of Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma (PDAC): A Multi-Institutional Study, 2020-12-05

• Early Detection of Pancreatic Cancer: Opportunities and Challenges, 2019-02-02

• Targeting TGF ßR2-mutant tumors exposes vulnerabilities to stromal TGF ß blockade in pancreatic cancer, 2019-10-14

• RNA sequencing-based analysis of gallbladder cancer reveals the importance of the liver X receptor and lipid metabolism in gallbladder cancer, 2016-05-05

• Prospective randomized double-blind study of atlas-based organ-at-risk autosegmentation-assisted radiation planning in head and neck cancer, 2014-09-09

• Radiation-induced liver disease and modern radiotherapy, 2019-01-12

• Hyperfractionated abdominal reirradiation for gastrointestinal malignancies, 2018-08-07

• A mathematical model for the quantification of a patient's sensitivity to checkpoint inhibitors and long-term tumour burden, 2021-01-04

• Quantitative imaging to evaluate malignant potential of IPMNs, 2016-08-31

• Pretreatment plasma HGF as potential biomarker for susceptibility to radiation-induced liver dysfunction after radiotherapy, 2018-10-18

• Early detection of pancreatic cancer, 2020-03-02

• Diminished Immune Surveillance During Histological Progression of Intraductal Papillary Mucinous Neoplasms offers a therapeutic opportunity for cancer interception, 2022-05-02

• Benchmarking Outcomes for Definitive Treatment of Young-Onset, Locally Advanced Rectal Cancer, 2021-10-09

• Enhancement pattern mapping technique for improving contrast-to-noise ratios and detectability of hepatobiliary tumors on multiphase computed tomography, 2019-11-19

• Prognosticators for Patients with Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant FOLFIRINOX or Gemcitabine/Nab-Paclitaxel Therapy and Pancreatectomy, 2023-05-04

• GRP78 Expression and Prognostic Significance in Patients with Pancreatic Ductal Adenocarcinoma Treated with Neoadjuvant Therapy Verse Surgery First, 2021-08-18

• Cancer overdiagnosis: a biological challenge and clinical dilemma, 2022-01-13

• PIONEER-Panc: a platform trial for phase II randomized investigations of new and emerging therapies for localized pancreatic cancer, 2022-01-03

• Definitive Intensity-Modulated Chemoradiation for Anal Squamous Cell Carcinoma: Outcomes and Toxicity of 428 Patients Treated at a Single Institution, 2022-01-28

• Radiomics for the Diagnosis and Differentiation of Pancreatic Cystic Lesions, 2020-07-21

• A visually apparent and quantifiable CT imaging feature identifies biophysical subtypes of pancreatic ductal adenocarcinoma, 2018-08-06

• Circulating Nucleic Acids Are Associated With Outcomes of Patients With Pancreatic Cancer, 2018-09-19