Dr. Christian Larsen, MD

• General Surgery

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• Emory University Hospital

  Fellowship Hospital

• Emory University Affiliated Hospitals Residency Program

  Residency Hospital

• Stanford University School Of Medicine

  Internship Hospital

• Emory University

  Medical School

• Woodruff Health Sciences Center Emory University, Vice President, Health Center Integration

• iChoose Kidney: a Clinical Decision Aid for Kidney Transplantation vs. Dialysis Treatment, 2015-10-29

• Integrin antagonists for transplant immunosuppression: panacea or peril?, 2015-10-30

• Anti-LFA-1 Therapy in a Nonhuman Primate Renal Transplant Model of Costimulation Blockade Resistant Rejection, 2016-01-14

• Fc-Silent Anti-CD154 Domain Antibody Effectively Prevents Non-Human Primate Renal Allograft Rejection, 2017-02-25

• Corticosteroids and Methotrexate as Adjuvants to Costimulation Blockade in Nonhuman Primate Renal Transplantation, 2019-05-07

• Lessons learned: Early termination of a randomized trial of calcineurin inhibitor and corticosteroid avoidance using Belatacept, 2017-07-03

• Interferon-gamma Dictates Allograft Fate via Opposing Effects on the Graft and on Recipient CD8 T-cell Responses1, 2009-01-01

• Transient CD86 expression on HCV specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling1, 2010-01-25

• CD40 Blockade Combines with CTLA4Ig and Sirolimus To Produce Mixed Chimerism in an MHC-defined Rhesus Macaque Transplant Model, 2011-09-19

• CMV Status Drives Distinct Trajectories of CD4+ T Cell Differentiation, 2021-04-15

• PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+T cells to transplanted tissue, 2008-10-15

• Avoidance of CNI and Steroids Using Belatacept - Results of the Clinical Trials in Organ Transplantation 16 Trial, 2020-07-13

• Enhanced Requirement for TNFR2 in Graft Rejection Mediated by Low Affinity Memory CD8+T Cells During Heterologous Immunity, 2016-08-01

• mTOR regulates memory CD8 T cell differentiation, 2009-06-21

• The impact of belatacept on third party HLA alloantibodies in highly sensitized kidney transplant recipients, 2019-10-08

• Targeting inflammation and immune activation to improve CTLA4-Ig-based modulation of transplant rejection, 2022-09-02

• Belatacept and Sirolimus Prolong Nonhuman Primate Renal Allograft Survival without a Requirement for Memory T Cell Depletion, 2013-01-11

• Regulatory T cells in lung transplantation-an emerging concept, 2011-03-20

• Dynamics of Human Regulatory T Cells in Lung Lavages of Lung Transplant Recipients1, 2009-08-27

• Pre-transplant antibody screening and anti-CD154 costimulation blockade promote long-term xenograft survival in a pig-to-primate kidney transplant model, 2015-04-03

• Heterologous Immunity Triggered by a Single, Latent Virus inMus musculus: Combined Costimulation- and Adhesion- Blockade Decrease Rejection, 2013-08-05

• Kinetics of antibody response to influenza vaccination in renal transplant recipients, 2019-01-18

• The use of microbiome restoration therapeutics to eliminate intestinal colonization with multi-drug resistant organisms, 2018-08-29

• An MHC-defined primate model reveals significant rejection of bone marrow after mixed-chimerism induction despite full MHC matching, 2010-09-17

• Longitudinal Evaluation of Cytopenias in the Renal Transplant Population, 2022-05-26

• Expanded Non-human Primate Tregs Exhibit A Unique Gene Expression Signature and Potently Downregulate Allo-immune Responses, 2008-09-17

• The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism But With A Significant Risk of CMV Reactivation and Disease in Rhesus Macaques, 2016-09-19

• CD45RB Status of CD8+T Cell Memory Defines T Cell Receptor Affinity and Persistence, 2020-02-04

• Evidence for Kidney Rejection after Combined Bone Marrow and Renal Transplantation Despite Ongoing Whole-blood Chimerism in Rhesus Macaques, 2012-05-29

• GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR ENHANCES HUMAN ISLET POST TRANSPLANTATION SURVIVAL, 2011-10-15

• Decreased Incidence of NSF in Patients on Dialysis After Changing Gadolinium Contrast-Enhanced MRI Protocols, 2013-06-05

• Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes, 2020-08-09

• Ebola Virus Disease: Experience and Decision Making for the First Patients outside of Africa, 2015-07-28

• High CTLA-4 Expression on Th17 Cells Results in Increased Sensitivity to CTLA-4 Coinhibition and Resistance to Belatacept, 2014-06-26

• Effect of the iChoose Kidney decision aid in improving knowledge about treatment options among transplant candidates: A randomized controlled trial, 2018-03-26

• Anti-CD40 Monoclonal Antibody Synergizes with CTLA-4 Ig in Promoting Long-Term Graft Survival in Murine Models of Transplantation1, 2009-07-10